Karyopharm Therapeutics Inc. (KPTI)
About Karyopharm Therapeutics Inc.
Karyopharm Therapeutics Inc is a commercial-stage pharmaceutical company focused on novel cancer therapies and dedicated to the discovery, development, and commercialization of drugs directed against nuclear export for the treatment of cancer and other diseases. The company conducts research focused on intracellular communication between the nucleus and cytoplasm and has developed small-molecule compounds that inhibit exportin 1 (XPO1), a nuclear export protein. It is focused on marketing XPOVIO (selinexor).
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Financial summary
- Revenue FY2025
- $146.1M
- Net income
- -$196.0M
- Total assets
- $108.4M
- Market cap
- $205.8M
- Operating margin
- -62.1%
- Net margin
- -134.2%
Source: SEC EDGAR · updated Jun 7, 2026
Revenue & profit trend
Financial statements
Income statement
- Revenue
- $146.1M
- Operating expenses
- $236.8M
- Operating income
- -$90.7M
- Income tax
- $43.0K
- Net income
- -$196.0M
- EPS (basic)
- $-17.93
- EPS (diluted)
- $-17.93
Balance sheet
- Total assets
- $108.4M
- Current assets
- $103.1M
- Total liabilities
- $401.3M
- Current liabilities
- $92.1M
- Shareholders’ equity
- -$292.9M
Cash flow
- Operating cash flow
- -$75.4M
- Investing cash flow
- $43.4M
- Financing cash flow
- $30.0M
- Net cash flow
- -$1.9M
Statements via Polygon.io (SEC filings)
15-minute delayed · data by Polygon.io
Past year · hover for prices
52-week range
- Market cap
- $205.8M
- EPS (diluted)
- $-17.93
- Shares outstanding
- 27.8M
- Open
- —
- Day range
- –
- Prev close
- —
- Volume
- —
- IPO date
- Nov 6, 2013
Karyopharm Therapeutics Inc. (KPTI) Stock Price
- Reported a net loss of $196.0M in FY2025.
- Revenue grew 35% from FY2020 to FY2025.
- Trading 31% below its 52-week high.
Automatically generated from public filings and market data. Informational only — not investment advice or a recommendation to buy or sell any security.
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Karyopharm Therapeutics Inc.: frequently asked questions
Is Karyopharm Therapeutics Inc. an American company?
Karyopharm Therapeutics Inc. is a US-based company headquartered in Newton, Massachusetts, listed in the americancompanies.com directory of American companies. Its American-origin credentials have not yet been independently verified.
Where is Karyopharm Therapeutics Inc. headquartered?
Karyopharm Therapeutics Inc. is headquartered in Newton, Massachusetts, United States.
Is Karyopharm Therapeutics Inc. publicly traded?
Yes — Karyopharm Therapeutics Inc. is a publicly traded company. Its stock trades under the ticker symbol KPTI on the NASDAQ.
What does Karyopharm Therapeutics Inc. do?
Karyopharm Therapeutics Inc. is an American Pharmaceuticals company in the Health & Beauty sector.
