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Spero Therapeutics, Inc.

$2.74 -2.84% NASDAQ: SPRO · 15-min delayed
  • CAMBRIDGE, Massachusetts
  • Public · NASDAQ: SPRO
  • 25 employees
$163.3MMarket cap
$12.6MRevenue · FY2025
$8.6MNet income
25Employees
SPRONASDAQ
2017IPO

About Spero Therapeutics, Inc.

Spero Therapeutics Inc is a clinical-stage biopharmaceutical firm. It focuses on identifying, developing, and commercializing novel treatments for MDR (Multi-drug-resistant) bacterial infections and rare diseases. The company's product candidate, tebipenem pivoxil hydrobromide or tebipenem HBr, is designed to be an oral carbapenem-class antibiotic for use in adults to treat MDR Gram-negative infections. It is also developing SPR720, a novel oral antibiotic designed for the treatment of a rare, orphan disease caused by pulmonary non-tuberculous mycobacterial infections, or NTM disease. It is also focused on SPR206, a next-generation polymyxin investigational product candidate being developed as an IV-administered medicine to treat MDR Gram-negative infections in the hospital.

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Reported figures

Financial summary

Revenue FY2025
$12.6M
Net income
$8.6M
Total assets
$68.9M
Market cap
$163.3M
Operating margin
9.5%
Net margin
12.8%

Source: SEC EDGAR · updated Jun 7, 2026

Multi-year

Revenue & profit trend

Revenue Net income
FY 2025

Financial statements

Income statement

Revenue
$66.8M
Operating expenses
$60.5M
Operating income
$6.3M
Income tax
$261.0K
Net income
$8.6M
EPS (basic)
$0.15
EPS (diluted)
$0.15

Balance sheet

Total assets
$68.9M
Current assets
$67.3M
Total liabilities
$9.9M
Current liabilities
$8.9M
Shareholders’ equity
$59.0M

Cash flow

Operating cash flow
-$12.6M
Net cash flow
-$12.6M

Statements via Polygon.io (SEC filings)

NASDAQ: SPRO
$2.74 -2.84%

15-minute delayed · data by Polygon.io

Past year

$0.57 $3.04

52-week range

Market cap
$163.3M
P/E ratio
18.3
EPS (diluted)
$0.15
Shares outstanding
59.6M
Open
Day range
Prev close
Volume
IPO date
Nov 2, 2017

Market data by Polygon.io · prices are 15-minute delayed

Auto-generated

At a glance

  • Profitable — net income of $8.6M in FY2025.
  • Revenue grew 266% from FY2021 to FY2025.
  • Trading 10% below its 52-week high.
  • Valued at a price-to-earnings (P/E) ratio of 18.3.

Automatically generated from public filings and market data. Informational only — not investment advice or a recommendation to buy or sell any security.

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