SPRUCE BIOSCIENCES, INC.
About SPRUCE BIOSCIENCES, INC.
Spruce Biosciences Inc is a late-stage biopharmaceutical company focused on developing and commercializing novel therapies for rare endocrine disorders with unmet medical needs. The company develops biologics and small-molecule product candidates aimed at addressing diseases with unmet medical needs and limited or no approved therapies. Its product candidate, TA-ERT for the treatment of Mucopolysaccharidosis Type IIIB (MPS IIIB), is a fusion protein comprised of recombinant human alpha-N-acetylglucosaminidase (rhNAGLU) intended as an enzyme replacement therapy for patients who lack rhNAGLU enzyme activity. TA-ERT is designed to restore rhNAGLU enzyme activity in the central nervous system following intracerebroventricular injection and promote clearance of heparan sulfate in the brain.
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Financial summary
- Revenue FY2025
- $0
- Net income
- -$39.0M
- Total assets
- $53.0M
- Market cap
- $138.8M
Source: SEC EDGAR · updated Jun 7, 2026
Revenue & profit trend
Financial statements
Income statement
- Revenue
- $0
- Operating expenses
- $36.5M
- Operating income
- -$36.5M
- Income tax
- $0
- Net income
- -$39.0M
- EPS (basic)
- $-50.83
- EPS (diluted)
- $-50.83
Balance sheet
- Total assets
- $53.0M
- Current assets
- $52.1M
- Total liabilities
- $10.5M
- Current liabilities
- $10.1M
- Shareholders’ equity
- $42.5M
Cash flow
- Operating cash flow
- -$33.3M
- Investing cash flow
- -$10.2M
- Financing cash flow
- $43.5M
- Net cash flow
- $0
Statements via Polygon.io (SEC filings)
15-minute delayed · data by Polygon.io
Past year
52-week range
- Market cap
- $138.8M
- EPS (diluted)
- $-50.83
- Shares outstanding
- 2.8M
- Open
- —
- Day range
- –
- Prev close
- —
- Volume
- —
- IPO date
- Oct 9, 2020
Market data by Polygon.io · prices are 15-minute delayed
At a glance
- Reported a net loss of $39.0M in FY2025.
- Trading 73% below its 52-week high.
Automatically generated from public filings and market data. Informational only — not investment advice or a recommendation to buy or sell any security.
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